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Hebei youze Biotechnology Co.,Ltd(expird)

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Hebei youze Biotechnology Co.,Ltd(expird)

Business Type:Trading Company

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Year Established:
2022
Home>>Products>>Ramipril CAS 87333-19-5 PRAMACE / Vesdil

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Hebei youze Biotechnology Co.,Ltd(expird)

Country: China (Mainland)

Business Type:Trading Company

Ramipril CAS 87333-19-5 PRAMACE / Vesdil

CAS NO.87333-19-5

  • FOB Price: USD: 6.80-8.60 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: D/A,D/P,T/T,Other
  • Available Specifications:

    High(1-50)KilogramHigh(51-500)Kilogram

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Product Details

Keywords

  • Ramipril
  • 87333-19-5
  • Vesdil

Quick Details

  • ProName: Ramipril CAS 87333-19-5 PRAMACE / Vesd...
  • CasNo: 87333-19-5
  • Molecular Formula: C23H32N2O5
  • Appearance: White crystalline powder
  • Application: Pharmaceutical Intermediates
  • DeliveryTime: Usually within 3-5 working days after ...
  • PackAge: Customized
  • Port: TianJin, Shanghai, Qingdao
  • ProductionCapacity: 2000 Metric Ton/Month
  • Purity: 99%
  • Storage: Sealed, cool and dry storage
  • Transportation: ShippingBY EMS, DHL, TNT, UPS, FEDEX O...
  • LimitNum: 1 Kilogram
  • Moisture Content: N/A
  • Impurity: N/A
  • N/A: N/A

Superiority

Our Advantage

1.Best quality with competitive price.

2.Quick shipping,delivery on time.

3.We have a pharmaceutical raw material production plant and a reagent R&D center.

4.Support multiple trading methods and payment.We support wire transfer, , Paypal or escrow  payment.

5.One to one business communication.

6.OEM/ODM Avaliable.

7.We offer convenient one-station purchasing service. Our professionaland thoughtful after-sales service eliminates your worries.

8.We has many years exporting experience in active pharmaceutical ingredient products.,Strictly on selecting raw materials.

Details

Quick Details 

Common Name Ramipril
CAS Number 87333-19-5 Molecular Weight 416.511
Density 1.2±0.1 g/cm3    Boiling Point 616.2±55.0 °C at 760 mmHg  
Molecular Formula C23H32N2O5 Melting Point 106-108°C
MSDS ChineseUSA Flash Point 326.4±31.5 °C

Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.Target: ACERamipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM [1]. Ramipril enhances the activity of ACE-associated CK2 and the phosphorylation of ACE Ser1270 in cultured endothelial cells, but is unable to activate JNK or stimulate the nuclear accumulation of c-Jun in endothelial cells expressing a S1270A ACE mutant or in ACE-deficient cells. Prolonged Ramipril treatment increases ACE expression in primary cultures of human endothelial cells and in vivo (mouse lung), which can be prevented by pretreatment with the JNK inhibitor SP600125 [2].Chronic in vivo administration of Ramipril to rats at a dosage that has similar hypotensive effects in vitro HUVECs significantly reduces the rate of LPS-induced apoptosis compared to the other ACE inhibitors, which contrasts with the apoptosis effect in vitro [3]. Ramipril inhibits systolic blood pressure (SBP) with IC50 of 1.97 mg/kg in spontaneously hypertensive rats (SHR). When in combination with AT1-receptor blockade by candesartan-cilexetil increases SBP reduction synergistically rather than additively [4].

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Packaging & Delivery

Delivery Detail: Usually within 3-5 working days after full payment.

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Our Company Profile 

Hebei Youze Biological Technology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.

Quality Best, Customer First" is what we adhering all the time, we have enjoyed a high reputation in the world market, mainly North America, Eastern Europe, Western Europe, South America,  and Southeast Asia.....United States,Canada,UnitedKingdom,Holland,Poland,Australia,India,Netherlands,Germany,New zealand,Ireland,Russia,Kazakhstan,south africa and so on, all these countriese have our customers. 

"Fast shipment, safety delivery" is our advantage. We successfully shipped many Raw materials, API, Steriods, and so on, to many countries in the world. Good feedback and repeat orders surport both our company and customers's development.

We are warmly welcome your visit, and test our quality and channel.

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