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Hebei youze Biotechnology Co.,Ltd(expird)

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Home>>Products>>Amiodarone HCl CAS 19774-82-4 2-Butyl-3-benzofuranyl4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

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Hebei youze Biotechnology Co.,Ltd(expird)

Country: China (Mainland)

Business Type:Trading Company

Amiodarone HCl CAS 19774-82-4 2-Butyl-3-benzofuranyl4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

CAS NO.19774-82-4

  • FOB Price: USD: 6.80-8.60 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: D/A,D/P,T/T,Other
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Product Details

Keywords

  • Amiodarone HCl
  • 19774-82-4
  • 2-Butyl-3-benzofuranyl4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

Quick Details

  • ProName: Amiodarone HCl CAS 19774-82-4 2-Butyl-...
  • CasNo: 19774-82-4
  • Molecular Formula: C25H30ClI2NO3
  • Appearance: White crystalline powder
  • Application: Pharmaceutical Intermediates
  • DeliveryTime: Usually within 3-5 working days after ...
  • PackAge: Customized
  • Port: TianJin, Shanghai, Qingdao
  • ProductionCapacity: 2000 Metric Ton/Month
  • Purity: 99%
  • Storage: Sealed, cool and dry storage
  • Transportation: ShippingBY EMS, DHL, TNT, UPS, FEDEX O...
  • LimitNum: 1 Kilogram
  • Moisture Content: N/A
  • Impurity: N/A
  • N/A: N/A

Superiority

Our Advantage

1.Best quality with competitive price.

2.Quick shipping,delivery on time.

3.We have a pharmaceutical raw material production plant and a reagent R&D center.

4.Support multiple trading methods and payment.We support wire transfer, , Paypal or escrow  payment.

5.One to one business communication.

6.OEM/ODM Avaliable.

7.We offer convenient one-station purchasing service. Our professionaland thoughtful after-sales service eliminates your worries.

8.We has many years exporting experience in active pharmaceutical ingredient products.,Strictly on selecting raw materials.

Details

Quick Details 

Common Name Amiodarone HCl
CAS Number 19774-82-4 Molecular Weight 681.773
Density 1.58 g/cm3 Boiling Point 635.1ºC at 760 mmHg
Molecular Formula C25H30ClI2NO3 Melting Point 154-158°C
MSDS ChineseUSA Flash Point 337.9ºC
Symbol GHS02 GHS06 GHS08 
GHS02, GHS06, GHS08
Signal Word Danger

Amiodarone is an antiarrhythmic drug for inhibition of ATP-sensitive potassium channel with IC50 of 19.1 μM. IC50 Value: 1.5 uM ( inhibit TBARS, LOOH and FPL formation)[1]in vitro: It was found that 10 uM amiodarone induces accumulation of ethidium bromide (5 ug/ml) in Saccharomyces cerevisiae cells. At the same time, in yeast cells with inactivated MDR genes, accumulation of ethidium bromide was 6-fold higher even without amiodarone. Addition of non-lethal concentrations of amiodarone to MDR-deficient cells caused an increase of intracellular ethidium bromide to the level, which was even lower than the level in amiodarone-treated wild-type cells [2]. Cells treated with amiodarone were seen to have detached from the dish, with cell rounding, cytoplasmic blebbing and irregularity in shape. An increase in the sub-G1 phase fraction, from 15.43 to 21.34% and 79.83% and a reduction in the G1 phase fraction, from 48.83 to 41.63% and 11.52%, were observed in cells treated with amiodarone at concentrations of 0.1 and 1 mM, respectively [3].in vivo: Chronic treatment with oral amiodarone for 4 weeks reduced i.p. when myocytes were dialyzed with patch-pipettes containing either 10 mM Na+ or 80 mM Na+. In myocytes from untreated rabbits, acute exposure to amiodarone in vitro reduced i.p. when patch pipettes contained 10 mM Na+ but had no effect on i.p. at 80 mM Na+. Amiodarone had no effect on the voltage dependence of the pump or the affinity of the pump for extracellular K+ either after chronic treatment or during acute exposure [4].Clinical trial: Continuous Versus Episodic Amiodarone Treatment for the Prevention of Permanent Atrial Fibrillation . Phase not specified
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Packaging & Delivery

Delivery Detail: Usually within 3-5 working days after full payment.

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Our Company Profile 

Hebei Youze Biological Technology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.

Quality Best, Customer First" is what we adhering all the time, we have enjoyed a high reputation in the world market, mainly North America, Eastern Europe, Western Europe, South America,  and Southeast Asia.....United States,Canada,UnitedKingdom,Holland,Poland,Australia,India,Netherlands,Germany,New zealand,Ireland,Russia,Kazakhstan,south africa and so on, all these countriese have our customers. 

"Fast shipment, safety delivery" is our advantage. We successfully shipped many Raw materials, API, Steriods, and so on, to many countries in the world. Good feedback and repeat orders surport both our company and customers's development.

We are warmly welcome your visit, and test our quality and channel.

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