Hebei youze Biotechnology Co.,Ltd(expird)
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Country: 
China (Mainland)
Business Type:Trading Company
CAS NO.156223-05-1
High(1-50)KilogramHigh(51-500)Kilogram
Our Advantage
1.Best quality with competitive price.
2.Quick shipping,delivery on time.
3.We have a pharmaceutical raw material production plant and a reagent R&D center.
4.Support multiple trading methods and payment.We support wire transfer, , Paypal or escrow payment.
5.One to one business communication.
6.OEM/ODM Avaliable.
7.We offer convenient one-station purchasing service. Our professionaland thoughtful after-sales service eliminates your worries.
8.We has many years exporting experience in active pharmaceutical ingredient products.,Strictly on selecting raw materials.
Quick Details
| Common Name | GTS-21 | ||
|---|---|---|---|
| CAS Number | 156223-05-1 | Molecular Weight | 381.30 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 485.6±45.0 °C at 760 mmHg |
| Molecular Formula | C19H22Cl2N2O2 | Melting Point | 216-217℃ (decomposition) |
| MSDS | USA | Flash Point | 247.5±28.7 °C |
GTS-21 dihydrochloride is a selective α7 nicotinic acetylcholine receptor agonist, has recently been established as a promising treatment for inflammation. Target: nAChRin vitro: GTS-21 is one of the most potent α7nAChR agonists, has been reported to attenuate pro-inflammatory cytokine production, improve outcomes in sepsis models, pancreatitis, and ischemia-reperfusion injury, and inhibit the production of endotoxin-induced TNF in lung tissue. In addition, recent studies have demonstrated that GTS-21 inhibits the activities of endothelial cells and monocyte macrophages, as well as the secretion of pro-inflammatory cytokines in peripheral blood samples, by regulating the JAK2-STAT3 pathway. [1] in vivo: In septic animals, GTS-21 significantly ameliorated GI motility, lowered systemic and colonic levels of IL-6, decreased colonic permeability, and decreased the number of positive cultures obtained from blood and mesenteric lymph nodes. Splenectomy prevented animals from developing sepsis-induced ileus. Chrna7 mice displayed a more severe septic phenotype, whereas GTS-21 remarkably was also beneficial in these animals. [2]
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Packaging & Delivery
Delivery Detail: Usually within 3-5 working days after full payment.
Payment Term
Our Company Profile
Hebei Youze Biological Technology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.
In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.
Quality Best, Customer First" is what we adhering all the time, we have enjoyed a high reputation in the world market, mainly North America, Eastern Europe, Western Europe, South America, and Southeast Asia.....United States,Canada,UnitedKingdom,Holland,Poland,Australia,India,Netherlands,Germany,New zealand,Ireland,Russia,Kazakhstan,south africa and so on, all these countriese have our customers.
"Fast shipment, safety delivery" is our advantage. We successfully shipped many Raw materials, API, Steriods, and so on, to many countries in the world. Good feedback and repeat orders surport both our company and customers's development.
We are warmly welcome your visit, and test our quality and channel.