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CAS NO.148553-50-8
99%+(1-10)Kilogram99%(1-10)Kilogram
Chinese Name: Pregabalin
Chinese synonym: Pregabalin; (3S) - 3-aminomethyl-5-methylhexanoic acid; (+ /) - pregabalin;
English Name: Pregabalin English synonyms: 3 (s) - (aminomethyl) -5-methylhexanoicacid; (3S)-3-(ChemicalbookAMINOMETHYL)-5-METHYLHEXANOICACID; PREGABALIN; Pregablin; 3-(Aminomethyl)-5-methyl-hexanoicacid; PREDNISOLONESODIUMPHOSPHATE; (R)-Pregabalin; (S)-Pregabalin
CAS No.: 148553-50-8
Molecular formula: c8h17no2
Molecular weight: 159.23
Introduction: Pregabalin belongs to non γ- GABA receptor agonist or antagonist is a new type of calcium channel regulator, which can block voltage dependent calcium channels and reduce the release of neurotransmitters. Clinically, it is mainly used for neuralgia related to diabetes peripheral neuropathy, post herpetic neuralgia and adjuvant treatment of adult partial seizures, generalized anxiety disorder, central neuralgia (including neuralgia associated with spinal cord injury, stroke and multiple sclerosis) and fibromyalgia.
Usage: Pregabalin is mainly used for the treatment of peripheral neuralgia and adjuvant treatment of localized seizures.
Preparation: the preparation method of pregabalin capsule has the following steps:
① Pass the pregabalin raw material on the swing granulator for 30 meshes (aperture 600 μ m) Screen, and then pass the pregabalin raw materials passing the 30 mesh sieve through the 60 mesh sieve (aperture 250 μ m) Screen and 80 mesh (aperture 180 μ m) Screen, take the pregabalin granular powder that has passed the 60 mesh sieve and the 80 mesh sieve, and set aside;
② Pass the lactose through 80 meshes (aperture 180) on the vibrating screen μ m) Screen and 120 mesh (aperture 120 μ m) Screen, take the lactose granular powder that has passed the 80 mesh sieve and the 120 mesh sieve of chemicalbook, and set aside;
③ First, the pregabalin granular powder obtained in step ① (D50 particle size is 180 μ m~220 μ m. D90 particle size 250 μ m~280 μ m) Mix it evenly with the adhesive on the multi-directional motion mixer, and then add the lubricant and the lactose particle powder obtained in step ② (D50 particle size is 120 μ m~140 μ m. D90 particle size is 160 μ m~180 μ m) Continue to mix evenly, and finally fill the evenly mixed materials directly on the automatic capsule filling machine to obtain pregabalin capsules.
Details
Quick Details
Common Name | Pregabalin | ||
---|---|---|---|
CAS Number | 148553-50-8 | Molecular Weight | 159.226 |
Density | 1.0±0.1 g/cm3 | Boiling Point | 274.0±23.0 °C at 760 mmHg |
Molecular Formula | C8H17NO2 | Melting Point | 194-196ºC |
MSDS |
Chinese USA |
Flash Point | 119.5±22.6 °C |
Symbol | GHS05, GHS08 |
Signal Word | Danger |
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Hebei Youze Biological Technology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.
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