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Hebei youze Biotechnology Co.,Ltd(expird)

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Hebei youze Biotechnology Co.,Ltd(expird)

Business Type:Trading Company

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Year Established:
2022
Home>>Products>>Ketoconazole CAS 65277-42-1 Micosin/Brizoral

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Hebei youze Biotechnology Co.,Ltd(expird)

Country: China (Mainland)

Business Type:Trading Company

Ketoconazole CAS 65277-42-1 Micosin/Brizoral

CAS NO.65277-42-1

  • FOB Price: USD: 6.80-8.60 /Kilogram Get Latest Price
  • Min.Order: 1 Kilogram
  • Payment Terms: D/A,D/P,T/T,Other
  • Available Specifications:

    High(1-50)KilogramHigh(51-500)Kilogram

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Product Details

Keywords

  • Ketoconazole
  • 65277-42-1
  • Brizoral

Quick Details

  • ProName: Ketoconazole CAS 65277-42-1 Micosin/Br...
  • CasNo: 65277-42-1
  • Molecular Formula: C26H28Cl2N4O4
  • Appearance: White crystalline powder
  • Application: Pharmaceutical Intermediates
  • DeliveryTime: Usually within 3-5 working days after ...
  • PackAge: Customized
  • Port: TianJin, Shanghai, Qingdao
  • ProductionCapacity: 2000 Metric Ton/Month
  • Purity: 99%
  • Storage: Sealed, cool and dry storage
  • Transportation: ShippingBY EMS, DHL, TNT, UPS, FEDEX O...
  • LimitNum: 1 Kilogram
  • Moisture Content: N/A
  • Impurity: N/A
  • N/A: N/A

Superiority

Our Advantage

1.Best quality with competitive price.

2.Quick shipping,delivery on time.

3.We have a pharmaceutical raw material production plant and a reagent R&D center.

4.Support multiple trading methods and payment.We support wire transfer, , Paypal or escrow  payment.

5.One to one business communication.

6.OEM/ODM Avaliable.

7.We offer convenient one-station purchasing service. Our professionaland thoughtful after-sales service eliminates your worries.

8.We has many years exporting experience in active pharmaceutical ingredient products.,Strictly on selecting raw materials.

Details

Quick Details 

Common Name Ketoconazole
CAS Number 65277-42-1 Molecular Weight 531.431
Density 1.4±0.1 g/cm3 Boiling Point 753.4±60.0 °C at 760 mmHg
Molecular Formula C26H28Cl2N4O4 Melting Point 146°C
MSDS ChineseUSA Flash Point 409.4±32.9 °C
Symbol GHS06 GHS08 GHS09 GHS06, GHS08, GHS09 Signal Word Danger

Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 and CYP24A1 inhibitor.Target: CYP3A4 CYP24A1Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections [1]. Ketoconazole also is a cytochrome P450 inhibitor [2].Ketoconazole (KTZ), on the antischistosomal potential of these quinolines against Schistosoma mansoni infection by evaluating parasitological, histopathological, and biochemical parameters. Mice were classified into 7 groups: uninfected untreated (I), infected untreated (II), infected treated orally with PZQ (1,000 mg/kg) (III), QN (400 mg/kg) (IV), KTZ (10 mg/kg)+QN as group IV (V), HF (400 mg/kg) (VI), and KTZ (as group V)+HF (as group VI) (VII). KTZ plus QN or HF produced more inhibition (P<0.05) in hepatic CYP450 (85.7% and 83.8%) and CYT b5 (75.5% and 73.5%) activities, respectively, than in groups treated with QN or HF alone. This was accompanied with more reduction in female (89.0% and 79.3%), total worms (81.4% and 70.3%), and eggs burden (hepatic; 83.8%, 66.0% and intestinal; 68%, 64.5%), respectively, and encountering the granulomatous reaction to parasite eggs trapped in the liver.[3] CYP24A1 inhibitor enhances antiproliferative effects, increases systemic calcitriol exposure, and promotes the activation of caspase-independent apoptosis pathway.[4]
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Packaging & Delivery

Delivery Detail: Usually within 3-5 working days after full payment.

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Our Company Profile 

Hebei Youze Biological Technology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.

Quality Best, Customer First" is what we adhering all the time, we have enjoyed a high reputation in the world market, mainly North America, Eastern Europe, Western Europe, South America,  and Southeast Asia.....United States,Canada,UnitedKingdom,Holland,Poland,Australia,India,Netherlands,Germany,New zealand,Ireland,Russia,Kazakhstan,south africa and so on, all these countriese have our customers. 

"Fast shipment, safety delivery" is our advantage. We successfully shipped many Raw materials, API, Steriods, and so on, to many countries in the world. Good feedback and repeat orders surport both our company and customers's development.

We are warmly welcome your visit, and test our quality and channel.

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