Keywords

• Exemestane(FCE 24304)
• 107868-30-4
• Exemestanum [INN-Latin]

Quick Details

• ProName: Exemestane(FCE 24304) CAS 107868-30-4 ...
• CasNo: 107868-30-4
• Molecular Formula: C20H24O2
• Appearance: White crystalline powder
• Application: Pharmaceutical Intermediates
• DeliveryTime: Usually within 3-5 working days after ...
• PackAge: Customized
• Port: TianJin, Shanghai, Qingdao
• ProductionCapacity: 2000 Metric Ton/Month
• Purity: 99%
• Storage: Sealed, cool and dry storage
• Transportation: ShippingBY EMS, DHL, TNT, UPS, FEDEX O...
• LimitNum: 1 Kilogram
• Moisture Content: N/A
• Impurity: N/A
• N/A: N/A

Superiority

Our Advantage

1.Best quality with competitive price.

2.Quick shipping,delivery on time.

3.We have a pharmaceutical raw material production plant and a reagent R&D center.

4.Support multiple trading methods and payment.We support wire transfer, , Paypal or escrow  payment.

5.One to one business communication.

6.OEM/ODM Avaliable.

7.We offer convenient one-station purchasing service. Our professionaland thoughtful after-sales service eliminates your worries.

8.We has many years exporting experience in active pharmaceutical ingredient products.,Strictly on selecting raw materials.

Details

Quick Details 

Common Name	Exemestane
CAS Number	107868-30-4	Molecular Weight	296.403
Density	1.1±0.1 g/cm3	Boiling Point	453.7±45.0 °C at 760 mmHg
Molecular Formula	C20H24O2	Melting Point	155.13°C
MSDS	ChineseUSA	Flash Point	169.0±25.7 °C
Symbol	GHS07, GHS08	Signal Word	Danger

Exemestane(FCE 24304) is an aromatase inhibitor, inhibits human placental and rat ovarian aromatase with IC50 of 30 nM and 40 nM, respectively.Target: AromataseApproved: October 2005Exemestane competitively inhibits and time-dependently inactivates of human placental aromatase with Ki of 4.3 nM. Exemestane displaces [3H]DHT from rat prostate androgen receptor with IC50 of 0.9 μM [1]. Exemestane (1 μM) increases alkaline phosphatase activity in hFOB and Saos-2 cells and induces the expression of MYBL2, OSTM1, HOXD11, ADCYAP1R1, and glypican 2 in hFOB cells [2]. Exemestane causes aromatase degradation in a dose-responsive manner in MCF-7aro cells [3].Exemestane increases lumbar spine BMD by 14.0% in OVX rats at dose of 100 mg/kg. Exemestane (100 mg/kg) and 17-hydroexemestane (20 mg/kg) significantly reduces an ovariectomy-induced increase in serum pyridinoline and serum osteocalcin in rats and causes significant reductions of serum cholesterol and low-density lipoprotein cholesterol inOVX rats [4].Exemestane (20 mg/kg/day s.c.) induces 26% complete (CR) and 18% partial (PR) tumor regressions in rats with 7,12-dimethylbenzanthracene (DMBA)-induced mammary tumors [5].

Main Product Image

Packaging & Delivery

Delivery Detail: Usually within 3-5 working days after full payment.

Payment Term

Our Company Profile 

Hebei Youze Biological Technology Co., Ltd. has a registered capital of 1 million yuan and is one of the most dynamic foreign trade companies in the Chinese market. We have a pharmaceutical raw material production plant and a reagent R&D center. We now have the most complete product line. In addition, we have developed and produced tens of thousands of reagents. We also have the business of custom synthesis of various organic compounds as a supplement. We can synthesize almost all chemicals. Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, Europe, South America, North America, Southeast Asia and Africa. We work with friends all over the world to develop the best quality products, the most reasonable prices and safe and effective transportation. Product can be ordered from milligrams to tons. Meet the purchase of new and old customers. We will not let you down.

Quality Best, Customer First" is what we adhering all the time, we have enjoyed a high reputation in the world market, mainly North America, Eastern Europe, Western Europe, South America,  and Southeast Asia.....United States,Canada,UnitedKingdom,Holland,Poland,Australia,India,Netherlands,Germany,New zealand,Ireland,Russia,Kazakhstan,south africa and so on, all these countriese have our customers. 

"Fast shipment, safety delivery" is our advantage. We successfully shipped many Raw materials, API, Steriods, and so on, to many countries in the world. Good feedback and repeat orders surport both our company and customers's development.

We are warmly welcome your visit, and test our quality and channel.